Luke Lee

Professor of Bioengineering; Director, Biomolecular Nanotechnology Center; Co-Director, Berkeley Sensor & Actuator Cente
Keywords: materials
Research Areas: biophysics, bionanotechnology, biophotonics, and BioMEMS (biomedical micro electro mechanical systems)

Research Description:

The BioPOETS (Biologically-inspired Photonics & Optofluidic Electronics Technology and Science) group is focusing on quantum nanoplasmonics for in vivo molecular and cellular imaging; microfluidic cellular BASICs (Biological Application Specific Integrated Circuits) for quantitative cell biology; soft-state biological devices for single cell biophysics; nanobiotechnology for molecular diagnostics; BioMEMS and BioPOEMS (Biomolecular Polymeric Opto-Electro Mechanical Systems) for the digitalization of quantitative systems biology, systematic neuroscience, and molecular medicine.

Selected Publications:

  • Philip J. Lee, Paul J. Hung, and Luke P. Lee. An Artificial Liver Sinusoid with a Microfluidic Endothelial-like Barrier for Primary Hepatocyte Culture. Biotechnology and Bioengineering, 97(5), 1340-6, 2007.
  • Philip J. Lee, Paul J. Hung, Vivek M. Rao, Luke P. Lee. Nanoliter Scale Microbioreactor Array for Quantitative Cell Biology. Biotechnology & Bioengineering, 94 (1), 5-14, 2006.
  • Ki-Hun Jeong, Jaeyoun Kim, Luke P. Lee. Biologically Inspired Artificial Compound Eyes. Science, 312, p. 557-561, 2006.
  • Luke P. Lee and Robert Szema. Inspirations from Biological Optics for Advanced Photonic Systems. Science, 310. no. 5751, pp. 1148 – 1150, 2005.
  • Cristian Ionescu-Zanetti, Robin M. Shaw, Jeonggi Seo, Yuh-Nung Jan, Lily Y. Jan, and Luke P. Lee. Mammalian Electrophysiology on a Microfluidic Platform. Proc. Natl. Acad. Sci. USA, June 20, 2005.
  • G. L. Liu, Y. Long, Y. Choi, T. Kang and L. P. Lee. Quantized Plasmon Quenching Dips
    Nanospectroscopy via Plasmon Resonance Energy Transfer. Nature Method, 4(12):1015-7, 2007.
  • G. L. Liu, J. Kim, Yu Lu and L. P. Lee. Optofluidic Control via Photothermal Nanoparticles.Nature Materials, 5(1), 27-32, 2006.
  • G. L. Liu, Y. Yin, Siri Kunchakarra, B. Mukherjee, D. Gerion, S. D. Jett, D. G. Bear, J. Gray, A. Paul Alivisatos, L. P. Lee, and F. Chen. A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting. Nature Nanotechnology, 1, 47-52, 2006.
  • Y. Lu, G. L. 2. G. L. Liu, Y. Lu, J. Kim, J. C. Doll, L. P. Lee. Magnetic Nanocrescents as Controllable Surface- Enhanced Raman Scattering Nanoprobes for Biomolecular Imaging. Advanced Materials, 17, 22, 2683-2688, 2005.
  • Liu, J. Kim, Y. X. Mejia, and L. P. Lee. Nanophotonic Crescent Moon Structures with Sharp Edge for Ultrasensitive Biomolecular Detections by Local Electromagnetic Field Enhancement Effect. Nano Letters, 5(1), 119-124 (2005).
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